SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB44750

Signal sequence   MRCVTRTRNWWRRAARMPRAGSSAWWVAVCKQVCT

Length  35

Organism  Homo sapiens (Human)

UniProt ID  Q6ZRU5,

Motif  1..35



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB44750.cif

Structure  SPKB44750.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4181.95544

Aliphatic index  47.42857143

Isoelectric point  12.38166439

Charge (pH=7)   7.811741939

Topological polar surface area  1753.74

Aromaticity  0.114285714

Average rotatable bonds  3.742857143

Number of hydrogen bond donors  71

Number of hydrogen bond acceptors  56

X logP energy  -17.82601

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.