SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB42256

Signal sequence   MRKVLRVKKNIKIARIVPLVLLLVA

Length  25

Organism  Streptococcus pyogenes serotype M18 (strain MGAS8232)

UniProt ID  Q8P2P8,

Motif  1..25



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Cell membrane

Secretion efficiency  NA

Type  Sec/SPII



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB42256.cif

Structure  SPKB42256.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2884.78304

Aliphatic index  190.8

Isoelectric point  12.82563986

Charge (pH=7)   6.99679423

Topological polar surface area  1085.8

Aromaticity  0

Average rotatable bonds  4.08

Number of hydrogen bond donors  39

Number of hydrogen bond acceptors  35

X logP energy  -2.83739

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.