SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB42255

Signal sequence   MGKKMSLILGAFLSVFLLVA

Length  20

Organism  Streptococcus pyogenes serotype M18 (strain MGAS8232)

UniProt ID  Q8P280,

Motif  1..20



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Cell membrane

Secretion efficiency  NA

Type  Sec/SPII



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB42255.cif

Structure  SPKB42255.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2138.74124

Aliphatic index  156

Isoelectric point  10.80537956

Charge (pH=7)   1.997394232

Topological polar surface area  708.72

Aromaticity  0.1

Average rotatable bonds  3.65

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  27

X logP energy  -1.2651

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.