SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB42218

Signal sequence   MKPWILLLVMFISGVVMLLPVLG

Length  23

Organism  Homo sapiens (Human)

UniProt ID  Q8NEX5,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB42218.cif

Structure  SPKB42218.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2570.37794

Aliphatic index  186.0869565

Isoelectric point  9.700002532

Charge (pH=7)   0.997689266

Topological polar surface area  747.98

Aromaticity  0.086956522

Average rotatable bonds  3.52173913

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  29

X logP energy  3.6792

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.