General Information
SPKB ID SPKB41051
Signal sequence MSKVTTVFIGALVLLLLIENGF
Length 22
Organism Ixodes holocyclus (Australian paralysis tick)
UniProt ID Q5UB45,
Motif 1..22
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB41051.cif
Physicochemical Information
Molecular weight 2378.93904
Aliphatic index 168.1818182
Isoelectric point 6.408795646
Charge (pH=7) -0.000535612
Topological polar surface area 841.52
Aromaticity 0.090909091
Average rotatable bonds 3.590909091
Number of hydrogen bond donors 29
Number of hydrogen bond acceptors 30
X logP energy -2.9859
Hydropathy 
Literature Information
Title Holocyclotoxin-1, a cystine knot toxin from Ixodes holocyclus.
DOI 10.1016/j.toxicon.2014.08.068,
Publication Year 2014
PubMed ID 25172536,
Patent ID NA,
