SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB40870

Signal sequence   MKHLRPQFPLILAIYCFCMLQIPSSG

Length  26

Organism  Homo sapiens (Human)

UniProt ID  Q5H8A3,

Motif  1..26



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB40870.cif

Structure  SPKB40870.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3007.72434

Aliphatic index  108.8461538

Isoelectric point  8.801024153

Charge (pH=7)   1.963795199

Topological polar surface area  1027.92

Aromaticity  0.115384615

Average rotatable bonds  3.615384615

Number of hydrogen bond donors  36

Number of hydrogen bond acceptors  39

X logP energy  -4.31593

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.