SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB38588

Signal sequence   MKQMNKLITGVVTLATVVTLSA

Length  22

Organism  Streptococcus pyogenes serotype M18 (strain MGAS8232)

UniProt ID  P60813,

Motif  1..22



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Cell membrane

Secretion efficiency  NA

Type  Sec/SPII



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB38588.cif

Structure  SPKB38588.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2318.85924

Aliphatic index  132.7272727

Isoelectric point  10.80537956

Charge (pH=7)   1.997394232

Topological polar surface area  913.79

Aromaticity  0

Average rotatable bonds  3.590909091

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  34

X logP energy  -8.5207

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.