SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB37727

Signal sequence   MAVIMVDQAEG

Length  11

Organism  Actinia equina (Beadlet anemone)

UniProt ID  P0DY21,

Motif  1..11



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB37727.cif

Structure  SPKB37727.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1163.36934

Aliphatic index  106.3636364

Isoelectric point  3.550073557

Charge (pH=7)   -1.999794094

Topological polar surface area  472.01

Aromaticity  0

Average rotatable bonds  3.545454545

Number of hydrogen bond donors  15

Number of hydrogen bond acceptors  17

X logP energy  -3.6132

Hydropathy 



Literature Information


Title  Equinins as Novel Broad-Spectrum Antimicrobial Peptides Isolated from the Cnidarian Actinia equina (Linnaeus, 1758).

DOI  10.3390/md22040172,

Publication Year  2024

PubMed ID  38667789,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.