SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB37649

Signal sequence   MMIKWIISILTMSIMPVLVYS

Length  21

Organism  Variola virus (isolate Human/India/Ind3/1967) (VARV) (Smallpox virus)

UniProt ID  P0DSY5,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB37649.cif

Structure  SPKB37649.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2470.18634

Aliphatic index  157.6190476

Isoelectric point  9.298300651

Charge (pH=7)   0.996838851

Topological polar surface area  779.49

Aromaticity  0.095238095

Average rotatable bonds  3.80952381

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  32

X logP energy  0.4066

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.