SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB35874

Signal sequence   MIIAFFLLIQCVYC

Length  14

Organism  Komagataella phaffii (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris)

UniProt ID  C4QYK3,

Motif  1..14



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB35874.cif

Structure  SPKB35874.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1677.15374

Aliphatic index  167.1428571

Isoelectric point  5.824052577

Charge (pH=7)   -0.126815547

Topological polar surface area  504.94

Aromaticity  0.214285714

Average rotatable bonds  3.714285714

Number of hydrogen bond donors  19

Number of hydrogen bond acceptors  20

X logP energy  1.919

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.