General Information
SPKB ID SPKB33591
Signal sequence MDSEAYPMKSSVKISQKKKASQDMAVICVWVMPLAVFGLIAIGQAAKTGQVQASSGSCAFHTLDGVAAESEGVRFIRLREDAQVGKEILRLQAYPRSTAALKGADASGDHKYFNLTEHNATTLVVSLARSLERLVDRDVPRNLLKFRILCAGKQEKLEEGSYLSITVYIEDVNDNAPEFLNVPYVVDVDENTSIESIIFEGVQAFDRDKPNTPNSEVHFSMSTVPEQLSADGSPYFALKSPHRPLLILKRELDFDNGIRQFKLPIFAWDRGTPANQANTTITINVRDVDDLPPKFTEGVYRTRINEFYPMTGVPIRIPLYFAPPIMAFDQDSLNASLVYDIISGNERQLFRVNPHNGVMYLQKEIDLEEESLPGNTFVLQLEARQKDNPLKKALARIEVEVLDLNDNVPEFEADYYNISIVENLPTGFSVLQVNAVDRDQGENSEFLYNLVETKDAAGAFRIDSRTGWITVRDDRLLDREQRRSIQLNVEALERNPSYLDDKHLKKPGPSKVQVEITLLDTNDNTPKFEHGNLYEFKVPINAPTGYVIGQVVAHDPDEGPNGHLLYELQRPKGSGYIPFRLDNKNGTIYVGGPLRRGRIAVFVEATDQPTNPSERRFSLAVITIEVYATIDDQAIDFVGAPYEFWVGANTPLGTSVGQVRTTLIYEGGDEIMYDLLHTYSEGVPFAIEERSGIITVIRELSEFKRKVYQFEAVANYLFANSSQSLVMSRSSSPLTTIASPAELSDEGVLITNLTIHIVNKPEQKVPLRPVIEEINMNVIHFHVEENVVGGIIGQLLYKNGINLVNNELGTYREMPSEPTSRNITMGSRFRSRNRSRSSKSKRRLPRRLVGDANIKLRYIIANQQEVVNKISITEDGTLLTLTGLDREQQPSYELTVIVEYSTGLVSGAGIYQVNIKVDDVNDNAPKFNALTYVGLINENCVVGTELSMNHAILIQDADEGPNAEFRVQLQGDYSDEFSIEYVNGTSSENSTHHKMPSTTGAFNIFNLTDQWNDEFKYQELHTTFMQTNFKLSSGPYFRISYTGKRGLDREKQQLYNLKIIAADTGGLSGYAHLTVLVADVNDNAPMFERISVFKDSRLEIREYTTDMEIYFVESSSGMTAPQATAAMMLAPPPYHIPGSPRFNVDRERSVGAGLGVVARAKSRRRMVRALTTKCPLFAIYEDTPVGTKVLQLSASDEDFGKNALLHYELQGEQVERTPGMPMLRVHGVKYFAIDKLSGELSVNYPLSANIEIMLNLTVTDIDGLKDSTCLRFTVMDVNNHAPTFKKSWYSFDTPEGEYKDSVLGQLTAIDMDFGENANITYTLSDSHLPFTIKPASGVLKIGGQLDRELKDKYSFQVIATDNAPVMQRMSSSVDVEVNVLDINDNRPEFIGYDDQTKAVKFIPSVADRTLMLPVYKAYLDRSTQPGTFVRQLTAIDKDNVGNGNGLVLYSIRHQEMQAPLFQIDSRDGTISTISRINGYNDYEHLNVSVIASDVGSPALSATAIVIVNLQGQAVTDPPKSTPKPEPPANVTVFQHAYYEVKLTENNEAPIEVMRLNLSAGLNPENYRWSLWLEEGLDETDAHPPFEYDAKNMLLYALKPFDREHISRYQLRIRADRLSREARNYARVSYPVVDERIEGLSLNECRILVHIADENDNAPKFRGNGQPIVAVLPQSASFGYPVTRVEANDLDEGLNAEIRYRLLNEPARLFGIDELSGNIRLLGELSRTEHIYGFDVKATDRMGADDGRSGIVNVFVYIINEAKQVRLVVAGMPVEVERRIEGLMEALSDAIGKDVRVRLLEPYSGGLEPATNAYIYAVDPHTNSIMEMEQLQDALAGLQLDALQLQQQKLDGGKPMPRILELAEFGQLARPAHASASSFMGGLEFVTVVLLALISLGALIAACCYVCMRQKRRLWSQRDFSASDAGLTYTIAGIGSPRGQKQRRQRQQRHTQRCSKGSTGSQRPTSAFMPESVCSSAQTQSTATATEKLEQQLHHHHQQQAMATQQQHHQYLNEQQRQQKREYIDVPLPKSIAKAAAVTSGGDGAVGVGSTPFVLKYNACQPVNNLNNYETSLFSLHSTGQDSGVEFLSSRELYETSPDSFQHGGSKRGNNTEVLCPRHAKAHLELRQPNTDSSDTYEDSLKTDEPLVAHNCRSANCEHRQHQQHPSHHPHYQNTRFEKRSCVRHSFSGVKDDLMQQSPQISLRPRGHALRNSMNDLEQRLHNLEQSFRRPLEFSKSNSLF
Length 100
Organism Drosophila melanogaster (Fruit fly)
UniProt ID Q9VEU1,
Motif 1..NA
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB33591.cif
Physicochemical Information
Molecular weight 250636.4557
Aliphatic index 85.39285714
Isoelectric point 5.643423645
Charge (pH=7) -49.91341814
Topological polar surface area 105332.78
Aromaticity 0.078571429
Average rotatable bonds 0.446428571
Number of hydrogen bond donors 1000
Number of hydrogen bond acceptors 1000
X logP energy -1102.93523
Hydropathy 
Literature Information
