SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB32693

Signal sequence   MAVVPLLLLGGLWSAVGA

Length  18

Organism  Homo sapiens (Human)

UniProt ID  Q99470,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB32693.cif

Structure  SPKB32693.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1767.20284

Aliphatic index  173.3333333

Isoelectric point  6.099999998

Charge (pH=7)   -0.002015701

Topological polar surface area  585.25

Aromaticity  0.055555556

Average rotatable bonds  2.944444444

Number of hydrogen bond donors  20

Number of hydrogen bond acceptors  21

X logP energy  -1.2321

Hydropathy 



Literature Information


Title  N-terminome analysis of the human mitochondrial proteome.

DOI  10.1002/pmic.201400617,

Publication Year  2015

PubMed ID  25944712,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.