SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB32319

Signal sequence   MHKEAEMLIGPQLDEKRWGWRLGDGSAAPPFLPQALSFLLLLPLASA

Length  47

Organism  Homo sapiens (Human)

UniProt ID  Q8WTU2,

Motif  1..47



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB32319.cif

Structure  SPKB32319.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  5173.08134

Aliphatic index  104.0425532

Isoelectric point  5.652065104

Charge (pH=7)   -0.905484963

Topological polar surface area  1927.44

Aromaticity  0.085106383

Average rotatable bonds  3.489361702

Number of hydrogen bond donors  64

Number of hydrogen bond acceptors  65

X logP energy  -11.37616

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.