SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB32149

Signal sequence   MKNSNKLIASVVTLASVMALAA

Length  22

Organism  Streptococcus pyogenes serotype M18 (strain MGAS8232)

UniProt ID  Q8P0E5,

Motif  1..22



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Cell membrane

Secretion efficiency  NA

Type  Sec/SPII



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB32149.cif

Structure  SPKB32149.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2232.72534

Aliphatic index  133.1818182

Isoelectric point  10.80537956

Charge (pH=7)   1.997394232

Topological polar surface area  893.56

Aromaticity  0

Average rotatable bonds  3.454545455

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  33

X logP energy  -9.2963

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.