SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB32117

Signal sequence   MDKVQSGFLILFLFLMECQLHLCLPYADG

Length  29

Organism  Homo sapiens (Human)

UniProt ID  Q8NEA5,

Motif  1..29



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB32117.cif

Structure  SPKB32117.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3346.03844

Aliphatic index  121.0344828

Isoelectric point  4.365985128

Charge (pH=7)   -2.033533399

Topological polar surface area  1162.57

Aromaticity  0.137931034

Average rotatable bonds  3.75862069

Number of hydrogen bond donors  40

Number of hydrogen bond acceptors  43

X logP energy  -3.7391

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.