SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB32004

Signal sequence   MWLQQRLKGLPGLLSSSWARRLLCLLGLLLLLLWFGGSGA

Length  40

Organism  Homo sapiens (Human)

UniProt ID  Q8IYS2,

Motif  1..40



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB32004.cif

Structure  SPKB32004.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4438.45034

Aliphatic index  151.25

Isoelectric point  12.22275045

Charge (pH=7)   3.935704616

Topological polar surface area  1615.62

Aromaticity  0.1

Average rotatable bonds  3.65

Number of hydrogen bond donors  60

Number of hydrogen bond acceptors  53

X logP energy  -7.15199

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.