SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB31377

Signal sequence   MRWPGNMERIVICLMVIFSGTVA

Length  23

Organism  Bos taurus (Bovine)

UniProt ID  Q76LU5,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB31377.cif

Structure  SPKB31377.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2624.23394

Aliphatic index  110

Isoelectric point  8.549845238

Charge (pH=7)   0.937778084

Topological polar surface area  955.17

Aromaticity  0.086956522

Average rotatable bonds  3.652173913

Number of hydrogen bond donors  35

Number of hydrogen bond acceptors  34

X logP energy  -5.19916

Hydropathy 



Literature Information


Title  Cloning, expression, and tissue distribution of bovine interleukin-21.

DOI  10.1016/s0165-2427(03)00106-5,

Publication Year  2003

PubMed ID  12969638,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.