SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB31356

Signal sequence   MKILEKALLENDSAAEEESRNLRTKR

Length  26

Organism  Macrothele gigas (Japanese funnel web spider)

UniProt ID  Q75WG5,

Motif  1..26



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB31356.cif

Structure  SPKB31356.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3045.46124

Aliphatic index  86.53846154

Isoelectric point  6.735429323

Charge (pH=7)   0.006411362

Topological polar surface area  1425.25

Aromaticity  0

Average rotatable bonds  4.307692308

Number of hydrogen bond donors  50

Number of hydrogen bond acceptors  45

X logP energy  -15.34669

Hydropathy 



Literature Information


Title  Rapid and efficient identification of cysteine-rich peptides by random screening of a venom gland cDNA library from the hexathelid spider Macrothele gigas.

DOI  10.1016/j.toxicon.2004.05.012,

Publication Year  2004

PubMed ID  15246762,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.