SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB27431

Signal sequence   MMGSFIFLLSIIISINYINSLHTVHRSNIHRNMHNGGM

Length  38

Organism  Dirofilaria immitis (Canine heartworm)

UniProt ID  P41974,

Motif  1..38



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB27431.cif

Structure  SPKB27431.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4370.15164

Aliphatic index  110.2631579

Isoelectric point  11.14786756

Charge (pH=7)   2.360763626

Topological polar surface area  1735.6

Aromaticity  0.078947368

Average rotatable bonds  3.842105263

Number of hydrogen bond donors  61

Number of hydrogen bond acceptors  61

X logP energy  -16.09776

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.