SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB26506

Signal sequence   MTRSALQMGRLTLVLCLLLQLVLVTQA

Length  27

Organism  Conus bayani (Bayan's cone) (Stellaconus bayani)

UniProt ID  P0DTJ3,

Motif  1..27



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB26506.cif

Structure  SPKB26506.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2985.74174

Aliphatic index  169.6296296

Isoelectric point  10.52640717

Charge (pH=7)   1.936002961

Topological polar surface area  1153.91

Aromaticity  0

Average rotatable bonds  3.777777778

Number of hydrogen bond donors  42

Number of hydrogen bond acceptors  40

X logP energy  -8.04906

Hydropathy 



Literature Information


Title  Diversity of Conopeptides and Conoenzymes from the Venom Duct of the Marine Cone Snail Conus bayani as Determined from Transcriptomic and Proteomic Analyses.

DOI  10.3390/md19040202,

Publication Year  2021

PubMed ID  33916793,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.