SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB26505

Signal sequence   MGRLTMALCWLLLLLLTTQA

Length  20

Organism  Conus bayani (Bayan's cone) (Stellaconus bayani)

UniProt ID  P0DTJ2,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB26505.cif

Structure  SPKB26505.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2261.87064

Aliphatic index  166

Isoelectric point  8.549912035

Charge (pH=7)   0.936006272

Topological polar surface area  797.69

Aromaticity  0.05

Average rotatable bonds  3.7

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  29

X logP energy  -2.51933

Hydropathy 



Literature Information


Title  Diversity of Conopeptides and Conoenzymes from the Venom Duct of the Marine Cone Snail Conus bayani as Determined from Transcriptomic and Proteomic Analyses.

DOI  10.3390/md19040202,

Publication Year  2021

PubMed ID  33916793,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.