SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB26460

Signal sequence   MRLAIILLLMTTIVLTIG

Length  18

Organism  Scorpiops pococki (Scorpion)

UniProt ID  P0DQN5,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB26460.cif

Structure  SPKB26460.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1985.60114

Aliphatic index  216.6666667

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  680.61

Aromaticity  0

Average rotatable bonds  3.722222222

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  25

X logP energy  -0.72603

Hydropathy 



Literature Information


Title  Immunosuppressive effects of a novel potassium channel toxin Ktx-Sp2 from Scorpiops Pocoki.

DOI  10.1186/s13578-019-0364-1,

Publication Year  2019

PubMed ID  31890149,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.