SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB26369

Signal sequence   MNPKLLIVIGLLLATGVCSFAKA

Length  23

Organism  Tityus serrulatus (Brazilian scorpion)

UniProt ID  P0DM29,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB26369.cif

Structure  SPKB26369.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2372.99644

Aliphatic index  156.9565217

Isoelectric point  9.676237541

Charge (pH=7)   1.935419516

Topological polar surface area  830.32

Aromaticity  0.043478261

Average rotatable bonds  3.391304348

Number of hydrogen bond donors  29

Number of hydrogen bond acceptors  31

X logP energy  -4.0406

Hydropathy 



Literature Information


Title  CPP-Ts: a new intracellular calcium channel modulator and a promising tool for drug delivery in cancer cells.

DOI  10.1038/s41598-018-33133-3,

Publication Year  2018

PubMed ID  30282983,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.