SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB26366

Signal sequence   MMSRLSVFILIALVLSVIIDVLNNSKVEG

Length  29

Organism  Olivierus martensii (Manchurian scorpion) (Mesobuthus martensii)

UniProt ID  P0DL65,

Motif  1..29



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB26366.cif

Structure  SPKB26366.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3174.89144

Aliphatic index  174.4827586

Isoelectric point  6.494323083

Charge (pH=7)   -0.0000924

Topological polar surface area  1207.74

Aromaticity  0.034482759

Average rotatable bonds  3.75862069

Number of hydrogen bond donors  42

Number of hydrogen bond acceptors  42

X logP energy  -7.48043

Hydropathy 



Literature Information


Title  Mesomartoxin, a new K(v)1.2-selective scorpion toxin interacting with the channel selectivity filter.

DOI  10.1016/j.bcp.2014.12.002,

Publication Year  2015

PubMed ID  25514171,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.