SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB26190

Signal sequence   MRLLILFLAVVTLLSLAGPGSAEV

Length  24

Organism  Ornithorhynchus anatinus (Duckbill platypus)

UniProt ID  P0C8B1,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB26190.cif

Structure  SPKB26190.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2484.07884

Aliphatic index  178.75

Isoelectric point  6.410149741

Charge (pH=7)   -0.000243889

Topological polar surface area  883.72

Aromaticity  0.041666667

Average rotatable bonds  3.333333333

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  31

X logP energy  -3.79653

Hydropathy 



Literature Information


Title  Defensins and the convergent evolution of platypus and reptile venom genes.

DOI  10.1101/gr.7149808,

Publication Year  2008

PubMed ID  18463304,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.