SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB25264

Signal sequence   MFSIPPSVRRLVFLFLIAAPLLSIVLPVAA

Length  30

Organism  Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487) (Filobasidiella neoformans var. grubii)

UniProt ID  J9VQE5,

Motif  1..30



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB25264.cif

Structure  SPKB25264.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3252.09424

Aliphatic index  169

Isoelectric point  12.50010931

Charge (pH=7)   1.997977677

Topological polar surface area  1056.55

Aromaticity  0.1

Average rotatable bonds  3.233333333

Number of hydrogen bond donors  36

Number of hydrogen bond acceptors  37

X logP energy  -1.41456

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.