SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB25098

Signal sequence   MNNLWKAWVGLWTSMGPLIRLPDGITKAGEDALRPWKSTAKHPWFEIEDNRCYIDNGKLFARGSIVGNMSRFVFDPKADYGGVGENLYVHADDVEFVPGESLKWNVRNLDVMPIFETLALRLVLQGDVIWLRCVPELRVDYTSSAYMWNMQYGMVRKSYTHVAWTIVFYSINITLLVLFIVYVTVDCNLSMMWMRFFVC

Length  100

Organism  Human cytomegalovirus (strain Merlin) (HHV-5) (Human herpesvirus 5)

UniProt ID  F5HE05,

Motif  1..NA



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB25098.cif

Structure  SPKB25098.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  23111.93824

Aliphatic index  94.42211055

Isoelectric point  6.764314109

Charge (pH=7)   -0.967678923

Topological polar surface area  8760.41

Aromaticity  0.145728643

Average rotatable bonds  3.713567839

Number of hydrogen bond donors  311

Number of hydrogen bond acceptors  297

X logP energy  -88.94183

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.