SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB25037

Signal sequence   MLPELLLARVLHPRAVICSFAIPGDPGDTCDTLSDRWGITIDIFKSLNPGVNCPNLVANMEYCVAGTVSPDTPSTTTTAKPTMTPTSTPTKTTTTSTATTTRAMTTTISSDAPSPTQPGLAKDCDKFHLVVSGDNCYSIQTKYGISTDQFKAWNPYINAECSNLWADYYVCVHVPGATISTSMPMPTPSGPQPQMPGIVSNCRKFHLIQAGDNCYTINQAVGITLAQFRSWNKNVNADCSNIWLGYYVCIGV

Length  100

Organism  Trichophyton rubrum (strain ATCC MYA-4607 / CBS 118892) (Athlete's foot fungus)

UniProt ID  F2ST24,

Motif  1..NA



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB25037.cif

Structure  SPKB25037.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  27161.88464

Aliphatic index  71.98412698

Isoelectric point  6.469952186

Charge (pH=7)   -2.380828682

Topological polar surface area  10852.72

Aromaticity  0.079365079

Average rotatable bonds  3.341269841

Number of hydrogen bond donors  381

Number of hydrogen bond acceptors  393

X logP energy  -181.27168

Hydropathy 



Literature Information


Title  Trichophyton rubrum LysM proteins bind to fungal cell wall chitin and to the N-linked oligosaccharides present on human skin glycoproteins.

DOI  10.1371/journal.pone.0215034,

Publication Year  2019

PubMed ID  30947244,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.