SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB23550

Signal sequence   MKTLLLTLVVVTIVCLDLGYT

Length  21

Organism  Pseudechis porphyriacus (Red-bellied black snake)

UniProt ID  A8HDJ4,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB23550.cif

Structure  SPKB23550.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2308.90384

Aliphatic index  185.2380952

Isoelectric point  6.157533513

Charge (pH=7)   -0.06468938

Topological polar surface area  809.79

Aromaticity  0.047619048

Average rotatable bonds  3.571428571

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  31

X logP energy  -2.5695

Hydropathy 



Literature Information


Title  Species differences in the neuromuscular activity of post-synaptic neurotoxins from two Australian black snakes (Pseudechis porphyriacus and Pseudechis colletti).

DOI  10.1016/j.toxlet.2013.03.026,

Publication Year  2013

PubMed ID  23545348,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.