SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB23331

Signal sequence   MSTFPVLAEDIPLRERHVKGRVDPHFRAPKMEMFQRLLLLLLLSMGGTWA

Length  50

Organism  Homo sapiens (Human)

UniProt ID  A6NKQ9,

Motif  1..50



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB23331.cif

Structure  SPKB23331.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  5805.96824

Aliphatic index  101.4

Isoelectric point  10.73325669

Charge (pH=7)   2.185414194

Topological polar surface area  2199.26

Aromaticity  0.08

Average rotatable bonds  3.8

Number of hydrogen bond donors  77

Number of hydrogen bond acceptors  74

X logP energy  -12.91285

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.