SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB22740

Signal sequence   MGIRLLCRVAFCFLAVGLVDVKVTQS

Length  26

Organism  Homo sapiens (Human)

UniProt ID  A0A5B6,

Motif  1..26



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB22740.cif

Structure  SPKB22740.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2839.51174

Aliphatic index  138.4615385

Isoelectric point  8.828052958

Charge (pH=7)   1.874179695

Topological polar surface area  1061.49

Aromaticity  0.076923077

Average rotatable bonds  3.615384615

Number of hydrogen bond donors  40

Number of hydrogen bond acceptors  37

X logP energy  -6.80166

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.