SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB22721

Signal sequence   MKCSVLQMSRLSWAMCLMLLMLLLLGTAQG

Length  30

Organism  Conus monile (Necklace cone)

UniProt ID  A0A4Y5X186,

Motif  1..30



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB22721.cif

Structure  SPKB22721.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3343.26034

Aliphatic index  133.3333333

Isoelectric point  8.828181491

Charge (pH=7)   1.873736522

Topological polar surface area  1178.03

Aromaticity  0.033333333

Average rotatable bonds  3.833333333

Number of hydrogen bond donors  44

Number of hydrogen bond acceptors  46

X logP energy  -6.53893

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.