SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB22443

Signal sequence   MGPGLLCWALLCLLGAGSVET

Length  21

Organism  Homo sapiens (Human)

UniProt ID  A0A0C4DH59,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB22443.cif

Structure  SPKB22443.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2104.56834

Aliphatic index  134.7619048

Isoelectric point  3.849941048

Charge (pH=7)   -1.12419001

Topological polar surface area  730.08

Aromaticity  0.047619048

Average rotatable bonds  3.095238095

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  28

X logP energy  -4.3269

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.