SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB22441

Signal sequence   MDWIWRILFLVGAATGAHS

Length  19

Organism  Homo sapiens (Human)

UniProt ID  A0A0C4DH39,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  7X7O,

Predicted Structure ID  SPKB22441.cif

Structure  SPKB22441.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2144.52174

Aliphatic index  113.1578947

Isoelectric point  7.550936504

Charge (pH=7)   0.089336563

Topological polar surface area  787.04

Aromaticity  0.157894737

Average rotatable bonds  3.421052632

Number of hydrogen bond donors  29

Number of hydrogen bond acceptors  26

X logP energy  -3.19173

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.