SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB22420

Signal sequence   METLLGLLILWLQLQWVSS

Length  19

Organism  Homo sapiens (Human)

UniProt ID  A0A0B4J279,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  8TW4,

Predicted Structure ID  SPKB22420.cif

Structure  SPKB22420.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2243.73234

Aliphatic index  179.4736842

Isoelectric point  3.849983241

Charge (pH=7)   -1.000240578

Topological polar surface area  802.87

Aromaticity  0.105263158

Average rotatable bonds  3.842105263

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  27

X logP energy  -1.2568

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.