SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB22406

Signal sequence   MKTFAGFSFLFLWLQLDCMSRG

Length  22

Organism  Homo sapiens (Human)

UniProt ID  A0A0B4J249,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB22406.cif

Structure  SPKB22406.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2599.12144

Aliphatic index  75.45454545

Isoelectric point  8.545113874

Charge (pH=7)   0.936157722

Topological polar surface area  919.21

Aromaticity  0.227272727

Average rotatable bonds  3.818181818

Number of hydrogen bond donors  34

Number of hydrogen bond acceptors  33

X logP energy  -4.32513

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.