SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB22357

Signal sequence   MDWTWRILFLVAAVTDAYS

Length  19

Organism  Homo sapiens (Human)

UniProt ID  A0A0A0MS14,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB22357.cif

Structure  SPKB22357.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2258.61974

Aliphatic index  107.8947368

Isoelectric point  4.109250254

Charge (pH=7)   -1.001976458

Topological polar surface area  836.12

Aromaticity  0.210526316

Average rotatable bonds  3.526315789

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  28

X logP energy  -3.00663

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.