SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB22329

Signal sequence   MAFWLRSLGLHFRPHLGRRMESFLGGVLLILWLQVDWVKS

Length  40

Organism  Homo sapiens (Human)

UniProt ID  A0A075B6T7,

Motif  1..40



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB22329.cif

Structure  SPKB22329.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4766.74044

Aliphatic index  121.75

Isoelectric point  12.05317719

Charge (pH=7)   3.181715809

Topological polar surface area  1746.16

Aromaticity  0.15

Average rotatable bonds  3.85

Number of hydrogen bond donors  64

Number of hydrogen bond acceptors  56

X logP energy  -6.11192

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.