SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB22328

Signal sequence   MKSLRVLLVILWLQLSWVWS

Length  20

Organism  Homo sapiens (Human)

UniProt ID  A0A075B6T6,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  7FJD,

Predicted Structure ID  SPKB22328.cif

Structure  SPKB22328.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2471.08794

Aliphatic index  180

Isoelectric point  11.65177567

Charge (pH=7)   1.997685954

Topological polar surface area  855.29

Aromaticity  0.15

Average rotatable bonds  3.95

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  28

X logP energy  0.45997

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.