General Information
SPKB ID SPKB22309
Signal sequence MDMRVPAQLLGLLLLWLPGVRF
Length 22
Organism Homo sapiens (Human)
UniProt ID A0A075B6H8,
Motif 1..22
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 8TFE,
Predicted Structure ID SPKB22309.cif
Physicochemical Information
Molecular weight 2539.18154
Aliphatic index 155
Isoelectric point 10.39776887
Charge (pH=7) 0.998424161
Topological polar surface area 876.82
Aromaticity 0.090909091
Average rotatable bonds 3.636363636
Number of hydrogen bond donors 30
Number of hydrogen bond acceptors 29
X logP energy -0.75146
Hydropathy
Literature Information