SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB22249

Signal sequence   MQIKHLITIFFLVLIVADHCHA

Length  22

Organism  Tityus serrulatus (Brazilian scorpion)

UniProt ID  S6D3A7,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB22249.cif

Structure  SPKB22249.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2563.16024

Aliphatic index  159.5454545

Isoelectric point  7.619880735

Charge (pH=7)   0.208888306

Topological polar surface area  887.1

Aromaticity  0.090909091

Average rotatable bonds  3.772727273

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  32

X logP energy  -1.4307

Hydropathy 



Literature Information


Title  Two peptides, TsAP-1 and TsAP-2, from the venom of the Brazilian yellow scorpion, Tityus serrulatus: evaluation of their antimicrobial and anticancer activities.

DOI  10.1016/j.biochi.2013.06.003,

Publication Year  2013

PubMed ID  23770440,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.