SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB21677

Signal sequence   MPSGCHSSPPSGLRGDMASLVPLSPYLSPTVLLLVSCDLGFVRA

Length  44

Organism  Homo sapiens (Human)

UniProt ID  Q9H6D8,

Motif  1..44



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB21677.cif

Structure  SPKB21677.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4529.32564

Aliphatic index  101.8181818

Isoelectric point  7.252287625

Charge (pH=7)   -0.03502011

Topological polar surface area  1691.26

Aromaticity  0.045454545

Average rotatable bonds  3.090909091

Number of hydrogen bond donors  60

Number of hydrogen bond acceptors  64

X logP energy  -17.84216

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.