General Information
SPKB ID SPKB21675
Signal sequence MQPTGREGSRALSRRYLRRLLLLLLLLLLRQPVTR
Length 35
Organism Homo sapiens (Human)
UniProt ID Q9H4B8,
Motif 1..35
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 6VGO,
Predicted Structure ID SPKB21675.cif
Physicochemical Information
Molecular weight 4160.08874
Aliphatic index 144.8571429
Isoelectric point 12.72241754
Charge (pH=7) 6.998882518
Topological polar surface area 1754.97
Aromaticity 0.028571429
Average rotatable bonds 4.057142857
Number of hydrogen bond donors 66
Number of hydrogen bond acceptors 53
X logP energy -13.66464
Hydropathy 
Literature Information
