SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB21657

Signal sequence   MEIISLKRFILLMLATSSLLT

Length  21

Organism  Bos taurus (Bovine)

UniProt ID  Q9GM96,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB21657.cif

Structure  SPKB21657.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2394.01234

Aliphatic index  171.9047619

Isoelectric point  9.695027686

Charge (pH=7)   0.999461077

Topological polar surface area  871.69

Aromaticity  0.047619048

Average rotatable bonds  3.952380952

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  32

X logP energy  -3.72643

Hydropathy 



Literature Information


Title  New neuropeptides containing carboxy-terminal RFamide and their receptor in mammals.

DOI  10.1038/35036326,

Publication Year  2000

PubMed ID  11025660,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.