SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB21219

Signal sequence   MKQKMMARLLRTSFALLFLGLFGVLGA

Length  27

Organism  Homo sapiens (Human)

UniProt ID  Q8WZ79,

Motif  1..27



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  Lysosome

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB21219.cif

Structure  SPKB21219.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3013.80054

Aliphatic index  122.962963

Isoelectric point  12.53174703

Charge (pH=7)   3.997387609

Topological polar surface area  1079.31

Aromaticity  0.111111111

Average rotatable bonds  3.851851852

Number of hydrogen bond donors  39

Number of hydrogen bond acceptors  38

X logP energy  -4.65376

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.