SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB21066

Signal sequence   MRKPAAGFLPSLLKVLLLPLAPAAA

Length  25

Organism  Homo sapiens (Human)

UniProt ID  Q8NEB7,

Motif  1..25



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB21066.cif

Structure  SPKB21066.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2559.23824

Aliphatic index  144.8

Isoelectric point  11.82305527

Charge (pH=7)   2.99739092

Topological polar surface area  860.73

Aromaticity  0.04

Average rotatable bonds  3.12

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  31

X logP energy  -2.70283

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.