SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB20373

Signal sequence   MRGAARAAWGRAGQPWPRPPAPGPPPPPLPLLLLLLAGLLGGAGA

Length  45

Organism  Homo sapiens (Human)

UniProt ID  Q641Q3,

Motif  1..45



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB20373.cif

Structure  SPKB20373.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4457.35764

Aliphatic index  98

Isoelectric point  12.97714556

Charge (pH=7)   3.997971054

Topological polar surface area  1569.3

Aromaticity  0.044444444

Average rotatable bonds  2.711111111

Number of hydrogen bond donors  50

Number of hydrogen bond acceptors  52

X logP energy  -10.53742

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.