SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB20282

Signal sequence   METGGRARTGTPQPAAPGVWRARPAGGGGGGASSWLLDGNSWLLCYGFLYLA

Length  52

Organism  Homo sapiens (Human)

UniProt ID  Q5VV63,

Motif  1..52



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB20282.cif

Structure  SPKB20282.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  5308.98354

Aliphatic index  64.03846154

Isoelectric point  9.323686707

Charge (pH=7)   1.936517117

Topological polar surface area  2129.85

Aromaticity  0.115384615

Average rotatable bonds  3.076923077

Number of hydrogen bond donors  77

Number of hydrogen bond acceptors  71

X logP energy  -23.55642

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.