SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB20139

Signal sequence   MAPRGCAGHPPPPSPQACVCPGKMLAMGALAGFWILCLLTYGYLSWGQA

Length  49

Organism  Homo sapiens (Human)

UniProt ID  Q5FYB0,

Motif  1..49



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB20139.cif

Structure  SPKB20139.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  5091.10904

Aliphatic index  75.91836735

Isoelectric point  8.335199633

Charge (pH=7)   1.838995353

Topological polar surface area  1734.1

Aromaticity  0.102040816

Average rotatable bonds  3

Number of hydrogen bond donors  61

Number of hydrogen bond acceptors  67

X logP energy  -12.42983

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.