SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB19427

Signal sequence   MPRVAIIIYTLYGHVAATAEA

Length  21

Organism  Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

UniProt ID  Q12335,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  5MP4,

Predicted Structure ID  SPKB19427.cif

Structure  SPKB19427.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2260.67954

Aliphatic index  125.7142857

Isoelectric point  7.535646471

Charge (pH=7)   0.088964373

Topological polar surface area  845.33

Aromaticity  0.095238095

Average rotatable bonds  3.238095238

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  30

X logP energy  -4.66703

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.